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Generic Substitution of Narrow Therapeutic Index Drugs
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Generic Substitution of Narrow Therapeutic Index Drugs | Generic interchange has become routine in pharmacy practice. |
Content Uniformity (CU) Criteria for Narrow Therapeutic Index (NTI) Drugs | Narrow Therapeutic Index NTI drugs require tighter control over content uniformity due to their narrow margin between therapeutic efficacy and toxicity. |
A Closer Look at Generic Interchangeability in Narrow Therapeutic Index Drugs | This article will examine what is considered an NTI drug, various laws related to NTI drugs, and position statements of national associations. |
Generic Substitution of Narrow Therapeutic Index Drugs | . |
- Content Uniformity (CU) Criteria for Narrow Therapeutic Index (NTI) Drugs • Narrow therapeutic index (NTI) drugs are drugs where small differences in dose or blood concentration may lead to serious therapeutic failures and/or adverse drug reactions .
- A Closer Look at Generic Interchangeability in Narrow Therapeutic Index Drugs Examples of NTI drugs that most people will be familiar with are the anticoagulant warfarin, which we know as the brand drug Coumadin®; and the synthetic hormone levothyroxine, which we .
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- Position Statements and Policies .